Developer Tools · Productivity
Variant File
Check
Run EBI's real vcf_validator conformance engine on a hosted VCF, with exact rule-and-line evidence — not just a parse
Variant File Check runs the same live engine here and in your assistant
Live playground
Use Variant File Check now
Point a tool at a public VCF URL and get the same engine-backed answer a connected assistant gets — the pinned EBI vcf_validator run over the real header and body, with exact rule, severity, and line evidence.
Your usage
—
Free forever — create a free account for a bigger monthly allowance that follows you across every app and every assistant.Pooled across every app and surface. Manage usage
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Marketplaces
Open Variant File Check where you already work — every listing runs the same live engine as this page.
- Marketplace listings are on the way. Meanwhile, point any MCP-compatible assistant straight at the live endpoint:
https://powmcp.com/variant-file-check/mcp
Proof
Real apps.Real engines.Real results.
- Application
- Variant File Check
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Engine Anatomy
Proof
Variant File Check
What it does
Run EBI's real vcf_validator conformance engine on a hosted VCF, with exact rule-and-line evidence — not just a parse
Validate one public VCF (.vcf or .vcf.gz) against the VCF specification and beyond-parse consistency — INFO/FORMAT definition-versus-usage, metadata-versus-body agreement, and header integrity — with exact rule, severity, and line evidence, or compare two same-lineage VCFs to show which findings changed, with a clear conformance-versus-biological-truth boundary.
Tools in this application
Variant File Check
variant_file_check
variant_file_check
Variant File Compare
variant_file_compare
variant_file_compare
0USD
Free to use with fair-use rate limits.
Variant File Check questions
Scope and boundaries for Variant File Check.
01What does Variant File Check actually check?
Validate one public VCF (.vcf or .vcf.gz) against the VCF specification and beyond-parse consistency — INFO/FORMAT definition-versus-usage, metadata-versus-body agreement, and header integrity — with exact rule, severity, and line evidence, or compare two same-lineage VCFs to show which findings changed, with a clear conformance-versus-biological-truth boundary.
02What does it never do?
It reports what its pinned engine measured and nothing more — it does not judge quality, correctness of your underlying business decisions, or anything outside its stated scope, and it never fabricates a result.
03What does it cost?
Nothing. Every published app is free to use with fair-use rate limits.
04Can my assistant connect directly?
Yes — any MCP-compatible assistant can connect straight to the canonical endpoint: https://powmcp.com/variant-file-check/mcp. Marketplace listings are conveniences over the same live engine.